Tuberculosis Research Paper

Tuberculosis Research Paper-25
In 2015, there were an estimated 1.8 million deaths due to tuberculosis, including HIV-associated tuberculosis deaths, making tuberculosis the leading cause of death from an infectious disease [1].

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What Awaits you: On-time delivery guarantee Masters and Ph D-level writers Automatic plagiarism check 100% Privacy and Confidentiality High Quality custom-written papers Use the order calculator below and get started!A simple cascade for tuberculosis transmission has been proposed in which (1) a source case of tuberculosis (2) generates infectious particles (3) that survive in the air and (4) are inhaled by a susceptible individual (5) who may become infected and (6) then has the potential to develop tuberculosis.Interventions that target these events will interrupt tuberculosis transmission and accelerate the decline in tuberculosis incidence and mortality.Individuals with index tuberculosis cases who are HIV infected, particularly those with advanced immunosuppression, were hypothesized to be less likely than HIV-uninfected individuals with tuberculosis to transmit to household contacts, possibly because of a greater likelihood of having smear-negative tuberculosis and a shorter duration of infectiousness due to more rapid progression to death [18, 19].Antiretroviral therapy reduces the risk of tuberculosis among people with HIV infection (PLHIV) by 67% and, if scaled up, may contribute to a reduction in tuberculosis case rates at a population level [20, 21].Nevertheless, scale-up of sputum smear microscopy has not succeeded in achieving dramatic declines in tuberculosis incidence.Possible reasons for the lack of impact include the poor sensitivity of smear microscopy, particularly among HIV-infected persons and children, and the occurrence of many cases of transmission before people receive a tuberculosis diagnosis and treatment.a-Synthesize relevant information, including research related to the diagnosis and treatment of the selected disorder.b-Recognize the assumptions inherent in the current literature and identify any unstated or missing information.In this series, a simple cascade for tuberculosis transmission is proposed in which (1) a source case of tuberculosis (2) generates infectious particles (3) that survive in the air and (4) are inhaled by a susceptible individual (5) who may become infected and (6) who then has the potential to develop tuberculosis.Interventions that target bacterial, host, or behavioral catalysts of transmission will interrupt tuberculosis transmission and accelerate the decline in tuberculosis incidence and mortality [14].

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